Curriculum Vitae:
Professor H. Oktay Seymen, MD
Professor of Physiology
Contact Details:
Phone: +90 (0) 212 414 3000 Ext.: 21559
Fax: +90 (0) 212 414 3072
E-mail: seymeno@istanbul.edu.tr
Web address: www.ctf.edu.tr/ctffizyo/oktayseymen/oktay.htm
Personal Profile: Professor Oktay Seymen is a Consultant Physiologist at the Department of Physiology, Cerrahpasa Medical Faculty at the University of Istanbul. He is also a Member of The American Physiological Society, The Society of Turkish Physiological Sciences and The International Free Radical Society. He has been a guest lecturer and visiting professor to a number of conferences and lectures in Turkey. He was a charter member of the ethical committee of experimental animals at Cerrahpasa Medical Faculty. He was the Editor of Cerrahpasa Journal of Medicine (2004 -2006). He is vice president of Dept. of Basic Medical Sciences of Cerrahpasa Medical Faculty. He is founder of Visual evoked potential recording laboratory at Cerrahpasa Medical Faculty.
Research
Interests: Professor Seymen's research interests include medical
interventional strategies in animal models of oxidant / antioxidant status of a
variety of diseases, new markers in some patho-physiological conditions, and
the development and use of novel technologies in electrophysiology and evoked
potentials. He has published widely in these and other areas related to
physiology and patho-physiological conditions. This work is based on long term
experimental process. Some of these areas of research have involved extensive
collaboration with the Departments of Biochemistry and Histopathology as well
as other physiology institutes in Europe and the United States of America.
Selected
Publications
Seymen
O.,
Seven A., Hatemi S., Hatemi H., Yiğit G., Candan G.: Lipid peroxidation in experimental
hyperthyroidism: effect of iron supplementation. Medical Science Research. 23(10): 695-696, 1995.
Seven A., Seymen O., Hatemi S., Hatemi H., Yiğit
G., Candan G.: Lipid peroxidation and vitamin E supplementation in experimental
hyperthyroidism. Clinical Chemistry.
42(7):1118-1119, 1996.
Seven A, Seymen O, Hatemi S., Hatemi H., Yiğit G., Candan G.: Antioxidant
Status in experimental hyperthyroidism: effect of vitamin E supplementation. Clinica Chimica Acta 256: 65-74, 1996.
Seymen
O.,
Seven A., Candan G., Yiğit G., Hatemi S., Hatemi H.: The effect of iron
supplementation on GSH levels, GSH-Px, and SOD activities of erythrocytes in
L-Thyroxine administration. Acta Medica
Okayama. 51 (3) : 129-133, 1997.
Seymen
HO,
Seven A, Civelek S, Yiğit G, Hatemi H, Burçak G: Evaluation of antioxidant
status in liver tissues: effect of iron supplementation in experimental
hyperthyroidism. J Basic &
Clinical Physiology & Pharmacology.
10(4):315-325,1999.
Seven A, Seymen O,
İnci F, Öz B, Yiğit G, Burçak G: Evaluation of oxidative stress in experimental
colitis: Effects of L-arginine-nitric oxide pathway manipulation. Journal of Toxicology and Environmental Health.
61(3):167-176, 2000.
Belce A, Uslu E, Kucur M,
Umut M, Ipbüker A, Seymen HO: Evaluation of Salivary Sialic Acid Level
and Cu - Zn Superoxide Dismutase
activity in Type 1 Diabetes Mellitus. Tohoku
J. Exp. Med.,192:219-225, 2000.
Civelek S, Seymen O, Seven A, Yiğit G, Hatemi H,
Burçak G.:Oxidative stress in heart
tissue of hyperthyroid and iron supplemented rats. Journal of Toxicology and Environmental Health Part
A, 64: 499-506, 2001.
Ünal M, Seymen HO: Effect of ringer-lactate and isotonic saline solutions
on mucociliary clearance of tracheal epithelium: an experimental study in rats.
The Journal of Laryngology &
Otology, July 2002, Vol 116, 2002.
Seven A, Güzel S, Seymen O, Civelek S, Bolayırlı M, Yiğit
G and Burçak G. Nitric oxide synthase inhibition by L-NAME in streptozotocin
induced diabetic rats: impacts on oxidative stress. Tohoku J. Exp. Med., 199, 205-210, 2003.
Andican G,
Gelisgen R, Civelek S, Seven A, Seymen O,
Altug T, Yigit G, Burcak G. : Oxidative
damage to nuclear DNA in hyperthyroid rat liver: inability of vitamin C to
prevent the damage. J Toxicol Environ Health A. 2004 Mar; 67(5): 413-20.
Seymen HO, Civelek S, Seven A, Yigit G, Hatemi H, Burcak G. Iron supplementation in experimental hyperthyroidism:
effects on oxidative stress in skeletal muscle tissue. Yonsei Med J. 2004 Jun; 45(3):413-8.
Seven A, Guzel S, Seymen O, Civelek S, Bolayirli M, Uncu
M, Burcak G.: Effects of vitamin E supplementation on oxidative stress in
streptozotocin induced diabetic rats: investigation of liver and plasma. Yonsei
Med J. 2004 Aug 31; 45(4):703-10.
Aytac E, Seymen H.O., Sozer V., Ozdemir M., Koc
N., Gumustas M.K, Altug T..: Effects of Iloprost on Lipid Peroxidation
Parameters in Cerebral Hypoperfusion Model Induced by Right Common Carotid
Artery Occlusion. International proceedings. 5th European Congress of
Oto-Rhino-Laryngology, Head and Neck Surgery. Rodos, Greece, September 11-16,
445-450. 2004.
Aytac E, Seymen HO, Uzun H, Dikmen G, Altug T. Effects of
iloprost on visual evoked potentials and brain tissue oxidative stress after
bilateral common carotid artery occlusion. Prostaglandins
Leukot Essent Fatty Acids. 2006
Jun;74(6):373-8.
Yildiz M, Masatlioglu S, Seymen P, Aytac E, Sahin B, Seymen HO. The
carotid-femoral (aortic) pulse wave velocity as a marker of arterial stiffness
in familial Mediterranean fever. Can J
Cardiol. 2006 Nov;22(13):1127-31.
Aytac
E, Seymen P, Dikmen G, Uzun H, Seymen HO.
Iloprost pretreatment before unilateral nephrectomy: An experimental study in
rats. Asian Journal of Surgery, 31(2):
69-74, April 2008.
Dedeoğlu
BD, Aytac E, Suzer O, Balci H, Uzun H, Seymen P, Seymen HO. Donor heart preservation with iloprost supplemented St.
Thomas Hospital cardioplegic solution in isolated rat hearts. Prostaglandins
Leukot Essent Fatty Acids, 2008 Jun;
78(6):415-21.
Up to date: Nov 15, 2008